I have Sonica Theater, and M-Audio's drivers made my system extremely unstable. I had constant freezes, sound problems and so on. I emailed M-Audio many times and asked them how to remove the drivers from my system. They responded (after a while), but never game me an answer on how to uninstall the driver, instead I things such as "we cannot reproduce your problem", "check that you are running the latest software"...

So I reinstalled Panther from Scratch and never installed any M-Audio drivers since. Panther recognizes Sonica Theater...and of course I cannot customize the speakers' settings, but at least the stability of my system is back.

Even though M-Audio says on their site that their drivers are compatible, I had to find out the hard way, that they have no clue...and probbaly will not even try to fix their software. Just see if their product is supported by the OS, and if so use it...otherwise be prepared for a long, and painful journey.