If you have a Retina MacBook Pro, you'll find a new checkbox in the Get Info window for an application: it says "Open in Low Resolution." This box is checked for Pages, for example. Unchecking it cleans up the text enormously. Why would the box be there and why is it checked for iWorks packages? (And is there any harm in unchecking it and getting clearer text?)
[kirkmc adds: Can't test this one, unless someone wants to send me a Retina MacBook Pro... If anyone has insight into the questions at the end of the hint, feel free to comment.]
Mac OS X Hints
http://hints.macworld.com/article.php?story=20120623192801218