MT-NewsWatcher (MTNW) allows only one signature per personality. This AppleScript will allow you to have a random script in each message -- however, you must manually run the script for each message.
property theFile : missing value tell application "MT-NewsWatcher" try set msg to message window 1 if theFile is missing value then set theFile to choose file with prompt "Choose the signatures file." set sig to some paragraph of (read theFile) set the signature of msg to the sig on error display alert "No outgoing message" message "You must have an outgoing message window open." as warning end try end tell
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