Here is a simple, safe AppleScript that ejects the Western Digital SmartWare VCD on start up. Paste this code into the AppleScript Editor, save it as an application, and add it to your login items in the Accounts System Preferences panel. Note that this does not remove the VCD; it just keeps it off your desktop.
tell application "Finder" activate try eject disk "WD SmartWare" end try end tell[robg adds: I haven't tested this one, as I don't have the software in question.]
Mac OS X Hints
http://hints.macworld.com/article.php?story=20100421204104397