One thing I hate about Safari 4 is the relocation of the reload button to the right side of the URL entry area. Sure, you can still use Command-R , but for those who prefer navigating with their mouse alone, here's a cool tip to somewhat solve your problem!
So, drag any of the buttons from my post to the far left of your bookmarks bar, and you've got a simple JavaScript reload button, just half an inch away from where the old one used to be! I've even been nice enough to create different designs using the "Special Characters..." dialog box in all Cocoa applications.
The simple javascript is:
javascript:location.reload(true)
I made them into buttons using some special characters like these: ⤶ ⌘ ⏎ ⎋
Mac OS X Hints
http://hints.macworld.com/article.php?story=20090627021328498