Recently, I noticed that whenever I right-clicked in any program, the beach ball would show up, and Force Quit would be my only option to close the offending app. After some digging, I figured out that the problem was with the DropBox contextual menu plug-in. I never use it so I just deleted it, but a later test showed that a reinstall also fixed the problem.
If you'd like to disable it on your system while troubleshooting contextual menu issues, you can find it here: ~/Library » Contextual Menu Items.
[robg adds: I've heard other reports of issues with the DropBox plug-in, so thought this might be worth sharing.]
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