Unfortunately, there's no uninstaller included with the disk image distribution. After some rooting around on the MacFUSE site, I found these removal instructions on the Issues tab. I'm posting this hint mainly to say that I indeed tried the removal script posted there, and it seems to have worked well. I also checked the programs listed in the removal script against my MacBook Pro (which hasn't ever had MacFUSE installed), and found no overalp (so nothing listed there is used by anything else). The only extra step I took was to also remove the MacFUSE receipts from /Library -> Receipts.
There's a lot of promise in MacFUSE, but I think I'll wait a couple generations before trying it again!

