Apple recently released a new version of the CHUD Tools (described near the bottom of the page; or just download from the CHUD FTP server), which provides a command-line tool called hwprefs that, among other things, allows the root user to enable or disable CPU napping.
I won't enter a debate as to whether it's better to create a StartupItem or add a line toward the end of /etc/rc to handle this, (or enter a debate as to whether or not it's a good idea to disable napping in general), but using this command...
hwprefs -v cpu_nap=false
...in either a StartupItem or /etc/rc will disable CPU napping at startup.

