The Postfix content filter is a complete tutorial for installing a shell script that links with a pipe to the main smtp prcess of your postfix server. It provides recipient protection, dropping viruses and spamming from mail queues.
[robg adds: I haven't tested this one, as it's well beyond my skill set and I don't run a local mail server, but I thought a few of you might find it interesting.]
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Mac OS X Hints
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